2010-04-29

Server outage

Due to some connection issues after server relocation, the web site was intermittently non-accessible this morning (European time). Fixed.

2010-04-20

Data Update

  • 24010 cases from 821 publications
  • 19152 CGH
  • 4817 array CGH

Re-intoduction of Single Case Ideograms

The case lists and array plotting interface allow now the direct plotting of chromosomal ideograms. The output is in SVG format; so users of Internet Explorer are out of luck, I guess. Never versions of Safari and Firefox work fine.

2010-04-02

Better Linking for Array Plot Options

  • clicking the GEO and EBI icons on top of the publication list will now search for all publications for which the EBI/GEO accession is known
  • the publication list will now better link to aCGH series available for plotting (sometimes those are linked through their PMID; those where not shown previously)

2010-03-31

New & Re-introduced Features

Some data analysis features have been made available (again), which had existed in some form in previous versions of the site. These are:

  • survival plots: data can now be filtered for cases with available clinical followup & survival information
  • KM-plots: for the cases with survival information, KM-plots can be generated displaying the difference in survival for changes involving genomic regions vs. the cases without those changes
  • circos plots, with optional limitation tho changes involving a specific region

2010-01-25

Code Updates

The code updates seem finished (pending bug reports). Among the new/improved implementations are:

  • the re-introduction of the ISCN ish cgh annotation converter (thanks to Nikolas Stoecklein for pushing me ...)
  • a multi-locus search as part of the "Locus Scores" engine as well as for the visualization & clustering part
  • improved performance (e.g. clustering 2000 cases @ 86 bands is now no problem, though still there is a soft limit somewhere near 5000, due to browser time-outs)
  • ...

Integration of this News blog into the site

Again a move of the "News & History" pages: With the introduction of this Wiki system, news will now be hosted here, abandoning progenetix.blogspot.com.

2009 and older